| Gene Information | |
|---|---|
| Gene Name | CYTH4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | Cytohesin-4 (PH, SEC7 and coiled-coil domain-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000100055 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UIA0 |
| Gene Card | CYTH4 |
| Uniprot ID | Q9UIA0 |
| Pfam | PF00169; PF01369 |
| In ASD | no |
| Allosteric Prediction | no (-0.355172615) |
| Ortholog in Animals | Alpaca_ CYTH4 ( ortholog_one2one ) Dog_ CYTH4 ( ortholog_one2one ) GuineaPig_ CYTH4 ( ortholog_one2one ) Macaque_ CYTH4 ( ortholog_one2one ) Mouse_ Cyth4 ( ortholog_one2one ) Pig_ CYTH4 ( ortholog_one2one ) Rat_ Cyth4 ( ortholog_one2one ) Rabbit_ CYTH4 ( ortholog_one2one ) |
| Ohnologs | CYTH3, CYTH2, CYTH1 |
| Paralogs | PSD2, PSD3, ARFGEF2, MON2, GBF1, ARFGEF1, PSD, PSD4, FBXO8, CYTH1, IQSEC3, IQSEC1, CYTH2, IQSEC2, CYTH3 |
| Tissue | adipose.tissue, spleen, whole.blood |
| Tissue Specificity | Expressed predominantly in peripheral blood leukocytes. {ECO:0000269|PubMed:10652308}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16998061 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17398095}; Peripheral membrane protein {ECO:0000269|PubMed:17398095}. |
| Mouse PG classification | NA |
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