| Gene Information | |
|---|---|
| Gene Name | SGTA |
| Organism | Homo sapiens (Human) |
| Gene Length | 313 |
| Protein Names | Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000104969 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43765 |
| Gene Card | SGTA |
| Uniprot ID | O43765 |
| Pfam | PF16546; PF00515; PF13181 |
| In ASD | no |
| Allosteric Prediction | no (-0.646457194) |
| Ortholog in Animals | Alpaca_ SGTA ( ortholog_one2one ) Dog_ SGTA ( ortholog_one2one ) GuineaPig_ SGTA ( ortholog_one2one ) Macaque_ SGTA ( ortholog_one2one ) Mouse_ Sgta ( ortholog_one2one ) Pig_ SGTA ( ortholog_one2one ) Rat_ Sgta ( ortholog_one2one ) |
| Ohnologs | SGTB |
| Paralogs | TTC1, TTC32, SUGT1, UNC45A, TTC4, TOMM34, SPAG1, SGTB, UNC45B, TOMM70, DNAAF4, TTC31, ST13, TTC12, STIP1, SPATA16, RPAP3, STUB1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VYI (X-ray 2.40A ) 4CPG (NMR - ) 4GOD (X-ray 1.40A ) 4GOE (X-ray 1.45A ) 4GOF (X-ray 1.35A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16580629}. Nucleus {ECO:0000269|PubMed:16580629}. Note=Co-localizes with HSP90AB1 in the cytoplasm. Increased nuclear accumulation seen during cell apoptosis. {ECO:0000269|PubMed:16580629}. |
| Mouse PG classification | NA |
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