| Gene Information | |
|---|---|
| Gene Name | DDX43 |
| Organism | Homo sapiens (Human) |
| Gene Length | 648 |
| Protein Names | Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000080007 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NXZ2 |
| Gene Card | DDX43 |
| Uniprot ID | Q9NXZ2 |
| Pfam | PF00270; PF00271; PF00013 |
| In ASD | no |
| Allosteric Prediction | no (-1.000371543) |
| Ortholog in Animals | Alpaca_ DDX43 ( ortholog_one2one ) Dog_ DDX43 ( ortholog_one2one ) Macaque_ DDX43 ( ortholog_one2one ) |
| Ohnologs | DDX53 |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, EIF4A2, DDX27, DDX46 |
| Tissue | testis |
| Tissue Specificity | Expressed in testis. Expressed in many tumors of various histological types at a level that is 100-fold higher than the level observed in normal tissues except testis. {ECO:0000269|PubMed:10919659}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs311686 rs311685 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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