| Gene Information | |
|---|---|
| Gene Name | SDC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 310 |
| Protein Names | Syndecan-1 (SYND1) (CD antigen CD138) |
| Target Name | syndecan-1 |
| Target Type | Clinical trial target |
| Gene Age | 810 ( ENSG00000115884 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P18827 |
| Gene Card | SDC1 |
| Uniprot ID | P18827 |
| Pfam | PF01034 |
| In ASD | no |
| Allosteric Prediction | yes (0.005939715) |
| Ortholog in Animals | Alpaca_ SDC1 ( ortholog_one2one ) Dog_ SDC1 ( ortholog_one2one ) GuineaPig_ SDC1 ( ortholog_one2one ) Macaque_ SDC1 ( ortholog_one2one ) Mouse_ Sdc1 ( ortholog_one2one ) Pig_ SDC1 ( ortholog_one2one ) Rat_ Sdc1 ( ortholog_one2one ) Rabbit_ SDC1 ( ortholog_one2one ) |
| Ohnologs | SDC4, SDC3 |
| Paralogs | SDC2, SDC4, SDC3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4GVC (X-ray 1.54A ) 4GVD (X-ray 1.85A ) 6EJE (X-ray 2.43A ) |
| DBSNP | rs2230922 rs10205485 |
| Subcellular location [CC] | Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:9169435}. Secreted, extracellular exosome {ECO:0000269|PubMed:22660413}. Note=Shedding of the ectodomain produces a soluble form. {ECO:0000269|PubMed:9169435}. |
| Mouse PG classification | NA |
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