| Gene Information | |
|---|---|
| Gene Name | SGK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 367 |
| Protein Names | Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000101049 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HBY8 |
| Gene Card | SGK2 |
| Uniprot ID | Q9HBY8 |
| Pfam | PF00069; PF00433 |
| In ASD | no |
| Allosteric Prediction | yes (0.401637642) |
| Ortholog in Animals | Alpaca_ SGK2 ( ortholog_one2one ) Dog_ SGK2 ( ortholog_one2one ) GuineaPig_ SGK2 ( ortholog_one2one ) Macaque_ SGK2 ( ortholog_one2one ) Mouse_ Sgk2 ( ortholog_one2one ) Pig_ SGK2 ( ortholog_one2one ) Rat_ Sgk2 ( ortholog_one2one ) |
| Ohnologs | SGK3, SGK1 |
| Paralogs | SGK3, STK32B, MAST3, STK32A, MAST2, LATS2, SGK1, MAST4, LATS1, STK32C, MAST1, DMPK, MASTL |
| Tissue | colon, kidney, cortex.of.kidney, liver, transverse.colon |
| Tissue Specificity | Highly expressed in liver, kidney and pancreas, and at lower levels in brain. {ECO:0000269|PubMed:10548550}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35793869 rs33969356 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21865597}. Nucleus {ECO:0000269|PubMed:21865597}. |
| Mouse PG classification | NA |
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