| Gene Information | |
|---|---|
| Gene Name | SEC13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 322 |
| Protein Names | Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000157020 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P55735 |
| Gene Card | SEC13 |
| Uniprot ID | P55735 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.207949296) |
| Ortholog in Animals | Alpaca_ SEC13 ( ortholog_one2one ) Dog_ SEC13 ( ortholog_one2one ) GuineaPig_ SEC13 ( ortholog_one2one ) Macaque_ SEC13 ( ortholog_one2one ) Mouse_ Sec13 ( ortholog_one2one ) Pig_ SEC13 ( ortholog_one2one ) Rat_ Sec13 ( ortholog_one2many ) Rabbit_ SEC13 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SEH1L |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.240851(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3BG0 (X-ray 3.15A ) 3BG1 (X-ray 3.00A ) 5A9Q (EM 23.00A ) 7PEQ (EM 35.00A ) 7R5K (EM 12.00A ) 7UHY (EM 3.66A ) |
| DBSNP | rs34078590 |
| Subcellular location [CC] | Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:8972206}; Peripheral membrane protein {ECO:0000269|PubMed:8972206}; Cytoplasmic side {ECO:0000269|PubMed:8972206}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:8972206}; Peripheral membrane protein {ECO:0000269|PubMed:8972206}; Cytoplasmic side {ECO:0000269|PubMed:8972206}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:14517296, ECO:0000269|PubMed:18160040}. Lysosome membrane {ECO:0000269|PubMed:28199306}. Note=In interphase, localizes at both sides of the NPC. {ECO:0000269|PubMed:14517296}. |
| Mouse PG classification | NA |
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