| Gene Information | |
|---|---|
| Gene Name | SFT |
| Organism | Homo sapiens (Human) |
| Gene Length | 147 |
| Protein Names | Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P51668 |
| Gene Card | UBE2D1 |
| Uniprot ID | P51668 |
| Pfam | PF00179 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Up-regulated in livers of iron-overloaded patients with hereditary hemochromatosis. {ECO:0000269|PubMed:12480712, ECO:0000269|PubMed:9362508}. |
| Pharmacological Animal Models | 0.013185(Chimpanzee);0.009187(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2C4P (X-ray 2.35A ) 2YHO (X-ray 2.10A ) 3OJ4 (X-ray 3.40A ) 3PTF (X-ray 2.70A ) 4AP4 (X-ray 2.21A ) 4QPL (X-ray 1.90A ) 5FER (X-ray 2.34A ) 5TUT (X-ray 2.60A ) 6D4P (X-ray 2.11A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18845142}. |
| Mouse PG classification | NA |
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