Gene Information
Gene NameHTMP10
OrganismHomo sapiens (Human)
Gene Length141
Protein NamesOpalin (Oligodendrocytic myelin paranodal and inner loop protein) (Transmembrane protein 10)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96PE5
Gene CardOPALIN
Uniprot IDQ96PE5
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityBrain specific;
expressed in oligodendrocytes (PubMed:11814680, PubMed:30837646). Expressed in oligodendrocytes in remyelinating multiple sclerosis plaques (PubMed:30837646). {ECO:0000269|PubMed:11814680, ECO:0000269|PubMed:30837646}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000250|UniProtKB:Q7M750};
Single-pass type I membrane protein {ECO:0000255}. Note=In the CNS, enriched in the myelin paranodal and inner loop membranes, but not that of the PNS. Enriched in the leading edge of extending processes. {ECO:0000250|UniProtKB:Q7M750}.
Mouse PG classificationNA
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