| Gene Information | |
|---|---|
| Gene Name | VPS13C |
| Organism | Homo sapiens (Human) |
| Gene Length | 3753 |
| Protein Names | Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000129003 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | VPS13C |
| Uniprot ID | Q709C8 |
| Pfam | PF09333; PF12624; PF06650; PF16908; PF16909; PF16910 |
| In ASD | no |
| Allosteric Prediction | no (-1.557617567) |
| Ortholog in Animals | Alpaca_ VPS13C ( ortholog_one2one ) Dog_ VPS13C ( ortholog_one2one ) GuineaPig_ VPS13C ( ortholog_one2one ) Macaque_ VPS13C ( ortholog_one2one ) Mouse_ Vps13c ( ortholog_one2one ) Pig_ VPS13C ( ortholog_one2one ) Rat_ Vps13c ( ortholog_one2one ) Rabbit_ VPS13C ( ortholog_one2one ) |
| Ohnologs | VPS13A |
| Paralogs | VPS13A, VPS13D |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15498460}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12595158 rs3784634 rs3784635 rs2303405 rs369100678 rs8026956 rs11629598 rs11629838 rs12907567 rs34060567 rs10851704 |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:26942284}. Lipid droplet {ECO:0000269|PubMed:30093493}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:30093493}. Lysosome membrane {ECO:0000269|PubMed:30093493}. Late endosome membrane {ECO:0000269|PubMed:30093493}. Note=May localize to endoplasmic reticulum-endolysosome contact sites. {ECO:0000269|PubMed:30093493}. |
| Mouse PG classification | NA |
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