Gene Information
Gene NameFASTKD5
OrganismHomo sapiens (Human)
Gene Length764
Protein NamesFAST kinase domain-containing protein 5, mitochondrial
Target NameNA
Target TypeNA
Gene Age3 ( ENSG00000215251 )
Evolutionary StageEumetazoa
AlphaFoldDBQ7L8L6
Gene CardFASTKD5
Uniprot IDQ7L8L6
PfamPF06743; PF08368; PF08373
In ASDno
Allosteric Predictionno (-0.660664471)
Ortholog in AnimalsAlpaca_ FASTKD5 ( ortholog_one2one )
Dog_ UBOX5 ( ortholog_one2one )
GuineaPig_ FASTKD5 ( ortholog_one2one )
Macaque_ FASTKD5 ( ortholog_one2one )
Mouse_ Fastkd5 ( ortholog_one2one )
Pig_ FASTKD5 ( ortholog_one2one )
Rat_ AABR07053741.1 ( ortholog_one2one )
OhnologsNA
ParalogsFASTKD3, FASTK, TBRG4, FASTKD2, FASTKD1
TissueNA
Tissue SpecificityExpression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid. {ECO:0000269|PubMed:20869947}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3746700  rs2422857  rs3746699 
Subcellular location [CC]Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:20869947, ECO:0000269|PubMed:25683715}. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. {ECO:0000269|PubMed:25683715}.
Mouse PG classificationNA
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