| Gene Information | |
|---|---|
| Gene Name | METTL7A |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | Putative methyltransferase-like protein 7A (EC 2.1.1.-) (Protein AAM-B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000185432 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H8H3 |
| Gene Card | METTL7A |
| Uniprot ID | Q9H8H3 |
| Pfam | PF08241 |
| In ASD | no |
| Allosteric Prediction | no (-0.215017659) |
| Ortholog in Animals | Alpaca_ METTL7A ( ortholog_one2one ) Dog_ METTL7A ( ortholog_one2one ) GuineaPig_ METTL7A ( ortholog_one2one ) Macaque_ METTL7A ( ortholog_one2one ) Mouse_ Mettl7a3 ( ortholog_one2many ) Mouse_ Mettl7a2 ( ortholog_one2many ) Mouse_ Mettl7a1 ( ortholog_one2many ) Pig_ METTL7A ( ortholog_one2one ) Rabbit_ METTL7A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | METTL7B, AS3MT, METTL27, COQ5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28372674 |
| Subcellular location [CC] | Lipid droplet {ECO:0000269|PubMed:18477614, ECO:0000269|PubMed:19773358, ECO:0000269|PubMed:26185986}. Endoplasmic reticulum {ECO:0000269|PubMed:19773358}. Membrane {ECO:0000269|PubMed:18477614}. Note=Inserted in the ER membrane and migrates from the inserted site to lipid droplet. {ECO:0000269|PubMed:18477614}. |
| Mouse PG classification | NA |
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