| Gene Information | |
|---|---|
| Gene Name | SF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 639 |
| Protein Names | Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162) |
| Target Name | splicing factor 1 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000168066 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15637 |
| Gene Card | SF1 |
| Uniprot ID | Q15637 |
| Pfam | PF00013; PF16275; PF00098 |
| In ASD | no |
| Allosteric Prediction | yes (0.116086857) |
| Ortholog in Animals | Alpaca_ SF1 ( ortholog_one2one ) Dog_ SF1 ( ortholog_one2one ) GuineaPig_ SF1 ( ortholog_one2one ) Macaque_ SF1 ( ortholog_one2one ) Mouse_ Sf1 ( ortholog_one2one ) Pig_ SF1 ( ortholog_one2one ) Rat_ Sf1 ( ortholog_one2one ) Rabbit_ SF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KHDRBS3, KHDRBS1, KHDRBS2, QKI |
| Tissue | NA |
| Tissue Specificity | Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart. {ECO:0000269|PubMed:7912130}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001169(Rat);0.018519(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1K1G (NMR - ) 1O0P (NMR - ) 1OPI (NMR - ) 2M09 (NMR - ) 2M0G (NMR - ) 4FXW (X-ray 2.29A ) 4FXX (X-ray 2.48A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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