| Gene Information | |
|---|---|
| Gene Name | SFTPA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 248 |
| Protein Names | Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000185303 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IWL1 |
| Gene Card | SFTPA2 |
| Uniprot ID | Q8IWL1 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | no (-0.968480756) |
| Ortholog in Animals | Alpaca_ SFTPA2 ( ortholog_one2one ) Mouse_ Sftpa1 ( ortholog_one2many ) Pig_ SFTPA1 ( ortholog_one2many ) Rat_ Sftpa1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | COLEC10, SFTPD, COLEC11, SFTPA1 |
| Tissue | lung |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1059046 rs72659394 rs192907309 rs17886395 rs121917738 rs1965708 rs121917737 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:26792177, ECO:0000269|PubMed:32855221}. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
| Mouse PG classification | NA |
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