Gene Information
Gene NameSET7
OrganismHomo sapiens (Human)
Gene Length366
Protein NamesHistone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8WTS6
Gene CardSETD7
Uniprot IDQ8WTS6
PfamPF02493; PF00856
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. Expressed in pancreatic islets. {ECO:0000269|PubMed:16141209}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.026087(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1H3I  (X-ray  2.10A  1MT6  (X-ray  2.20A  1MUF  (X-ray  2.26A  1N6A  (X-ray  1.70A  1N6C  (X-ray  2.30A  1O9S  (X-ray  1.75A  1XQH  (X-ray  1.75A  2F69  (X-ray  1.30A  3CBM  (X-ray  1.69A  3CBO  (X-ray  1.65A  3CBP  (X-ray  1.42A  3M53  (X-ray  1.85A  3M54  (X-ray  1.60A  3M55  (X-ray  1.55A  3M56  (X-ray  1.65A  3M57  (X-ray  1.70A  3M58  (X-ray  1.40A  3M59  (X-ray  1.70A  3M5A  (X-ray  1.75A  3OS5  (X-ray  1.69A  3VUZ  (X-ray  2.50A  3VV0  (X-ray  2.00A  4E47  (X-ray  2.00A  4J7F  (X-ray  1.59A  4J7I  (X-ray  2.56A  4J83  (X-ray  1.70A  4J8O  (X-ray  1.63A  4JDS  (X-ray  1.70A  4JLG  (X-ray  1.90A  5AYF  (X-ray  2.00A  5EG2  (X-ray  1.55A  5YLT  (X-ray  1.69A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000305|PubMed:11779497}. Chromosome {ECO:0000305|PubMed:11850410}.
Mouse PG classificationNA
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