| Gene Information | |
|---|---|
| Gene Name | SESN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 492 |
| Protein Names | Sestrin-1 (EC 1.11.1.-) (p53-regulated protein PA26) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000080546 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6P5 |
| Gene Card | SESN1 |
| Uniprot ID | Q9Y6P5 |
| Pfam | PF04636 |
| In ASD | no |
| Allosteric Prediction | no (-0.010685402) |
| Ortholog in Animals | Alpaca_ SESN1 ( ortholog_one2one ) Dog_ SESN1 ( ortholog_one2one ) GuineaPig_ SESN1 ( ortholog_one2one ) Macaque_ SESN1 ( ortholog_one2one ) Mouse_ Sesn1 ( ortholog_one2one ) Pig_ SESN1 ( ortholog_one2one ) Rat_ Sesn1 ( ortholog_one2one ) Rabbit_ SESN1 ( ortholog_one2one ) |
| Ohnologs | SESN3, SESN2 |
| Paralogs | SESN2, SESN3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12607115}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2273668 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9926927}. Cytoplasm {ECO:0000269|PubMed:15105503}. |
| Mouse PG classification | NA |
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