Gene Information
Gene NameSPAG11B
OrganismHomo sapiens (Human)
Gene Length103
Protein NamesSperm-associated antigen 11B (Human epididymis-specific protein 2) (He2) (Protein EP2) (Sperm antigen HE2)
Target NameNA
Target TypeNA
Gene Age3 ( ENSG00000164871 )
3 ( ENSG00000274405 )
3 ( ENSG00000288309 )
Evolutionary StageMammalia
AlphaFoldDBQ08648
Gene CardSPAG11B
Uniprot IDQ08648
PfamPF05324
In ASDno
Allosteric Predictionno (-1.303427956)
Ortholog in AnimalsAlpaca_ SPAG11B ( ortholog_one2many )
Dog_ SPAG11B ( ortholog_one2many )
Mouse_ Spag11b ( ortholog_one2many )
Rat_ Spag11bl ( ortholog_many2many )
OhnologsNA
ParalogsSPAG11A
TissueNA
Tissue SpecificitySpecifically expressed in caput and proximal corpus of epididymis (at protein level) (PubMed:8167223). Present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head (at protein level) (PubMed:8167223). {ECO:0000269|PubMed:8167223}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2853658  rs2738035 
Subcellular location [CC]Secreted {ECO:0000305}.
Mouse PG classificationNA
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