| Gene Information | |
|---|---|
| Gene Name | SERPINA12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 414 |
| Protein Names | Serpin A12 (OL-64) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (Visceral adipose-specific serpin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000165953 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8IW75 |
| Gene Card | SERPINA12 |
| Uniprot ID | Q8IW75 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | yes (0.281776355) |
| Ortholog in Animals | Alpaca_ SERPINA12 ( ortholog_one2one ) Dog_ SERPINA12 ( ortholog_one2one ) GuineaPig_ SERPINA12 ( ortholog_one2one ) Macaque_ SERPINA12 ( ortholog_one2one ) Mouse_ Serpina12 ( ortholog_one2one ) Pig_ SERPINA12 ( ortholog_one2one ) Rat_ Serpina12 ( ortholog_one2one ) Rabbit_ SERPINA12 ( ortholog_one2one ) |
| Ohnologs | SERPIND1 |
| Paralogs | SERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Expressed in visceral adipose tissues. {ECO:0000269|PubMed:16030142}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4IF8 (X-ray 2.08A ) 4Y3K (X-ray 2.20A ) 4Y40 (X-ray 2.20A ) 5EI0 (X-ray 2.50A ) |
| DBSNP | rs17090972 rs192558870 rs34519784 |
| Subcellular location [CC] | Secreted {ECO:0000305|PubMed:28668641}. |
| Mouse PG classification | NA |
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