| Gene Information | |
|---|---|
| Gene Name | SERPINB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 390 |
| Protein Names | Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000206073 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P48594 |
| Gene Card | SERPINB4 |
| Uniprot ID | P48594 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | no (-0.634098952) |
| Ortholog in Animals | Alpaca_ SERPINB4 ( ortholog_one2one ) Mouse_ Serpinb3d ( ortholog_many2many ) Mouse_ Serpinb3a ( ortholog_many2many ) Mouse_ Serpinb3b ( ortholog_many2many ) Mouse_ Serpinb3c ( ortholog_many2many ) Rat_ Serpinb3a ( ortholog_many2many ) Rat_ Serpinb3 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | SERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2, SERPINB3 |
| Tissue | esophagus, cervix, tongue, esophagus.mucosa, vagina |
| Tissue Specificity | Squamous cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10956412}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level. |
| Mouse PG classification | NA |
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