| Gene Information | |
|---|---|
| Gene Name | MCHR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 340 |
| Protein Names | Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCH-R2) (MCHR-2) (G-protein coupled receptor 145) (GPRv17) (MCH-2R) (MCH2) (MCH2R) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000152034 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q969V1 |
| Gene Card | MCHR2 |
| Uniprot ID | Q969V1 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.912354395) |
| Ortholog in Animals | Alpaca_ MCHR2 ( ortholog_one2one ) Dog_ MCHR2 ( ortholog_one2one ) Macaque_ MCHR2 ( ortholog_one2one ) Pig_ MCHR2 ( ortholog_one2one ) |
| Ohnologs | MCHR1, SSTR4, SSTR1, SSTR2 |
| Paralogs | MCHR1, TACR2, OR9A2, NPY1R, MTNR1B, OR11H6, OR11H7, OR11H4, OR9A1P, OR9G1, NPY2R, MTNR1A, GPR50, GPR75, OR11G2, GPR19, OR11A1, TACR1, TACR3, OR11H2, OR11H12, OR11H1, GPR83, PROKR2, PROKR1, GPR88, PRLHR, OR51F1, OR10X1, NPY5R, OR9A4, NPY4R2, NPY4R |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in the brain, with highest levels in cerebral cortex, hippocampus and amygdala. No expression detected in the cerebellum, thalamus or hypothalamus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs147988902 rs62434070 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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