| Gene Information | |
|---|---|
| Gene Name | NID2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1375 |
| Protein Names | Nidogen-2 (NID-2) (Osteonidogen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000087303 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14112 |
| Gene Card | NID2 |
| Uniprot ID | Q14112 |
| Pfam | PF12662; PF12947; PF07645; PF07474; PF00058; PF06119; PF00086 |
| In ASD | no |
| Allosteric Prediction | no (-1.350513604) |
| Ortholog in Animals | Alpaca_ NID2 ( ortholog_one2one ) Dog_ NID2 ( ortholog_one2one ) GuineaPig_ NID2 ( ortholog_one2one ) Macaque_ NID2 ( ortholog_one2one ) Mouse_ Nid2 ( ortholog_one2one ) Pig_ NID2 ( ortholog_one2one ) Rat_ Nid2 ( ortholog_one2one ) Rabbit_ NID2 ( ortholog_one2one ) |
| Ohnologs | NID1 |
| Paralogs | LDLR, LRP12, LRP2, EGF, LRP1, VLDLR, LRP4, LRP5, LRP1B, LRP6, LRP3, LRP8, LRP10, NID1 |
| Tissue | NA |
| Tissue Specificity | Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3920038 rs17124969 rs35657569 rs2101919 rs17831525 rs3742536 rs35147930 rs2273430 rs10134590 rs7144523 rs28507587 rs1305582875 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix, basement membrane. |
| Mouse PG classification | NA |
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