| Gene Information | |
|---|---|
| Gene Name | SERGEF |
| Organism | Homo sapiens (Human) |
| Gene Length | 458 |
| Protein Names | Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000129158 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UGK8 |
| Gene Card | SERGEF |
| Uniprot ID | Q9UGK8 |
| Pfam | PF00415 |
| In ASD | no |
| Allosteric Prediction | no (-0.824975377) |
| Ortholog in Animals | Alpaca_ SERGEF ( ortholog_one2one ) Dog_ SERGEF ( ortholog_one2one ) GuineaPig_ SERGEF ( ortholog_one2one ) Macaque_ SERGEF ( ortholog_one2one ) Mouse_ Sergef ( ortholog_one2one ) Pig_ SERGEF ( ortholog_one2one ) Rat_ Sergef ( ortholog_one2one ) Rabbit_ SERGEF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RCC2, RCBTB2, RCBTB1, RCC1L, RPGR, RCCD1, HERC1, RCC1, ALS2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1528 rs10788 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10571079}. Nucleus {ECO:0000269|PubMed:10571079}. |
| Mouse PG classification | NA |
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