| Gene Information | |
|---|---|
| Gene Name | SAST |
| Organism | Homo sapiens (Human) |
| Gene Length | 1570 |
| Protein Names | Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y2H9 |
| Gene Card | MAST1 |
| Uniprot ID | Q9Y2H9 |
| Pfam | PF08926; PF17820; PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal brain. {ECO:0000269|PubMed:30449657}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2M9X (NMR - ) 3PS4 (X-ray 1.85A ) |
| DBSNP | rs878853165 rs1568408280 rs1568409494 rs1568413207 rs35052801 rs1411105125 rs35071862 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9R1L5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9R1L5}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9R1L5}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9R1L5}. Cell projection, axon {ECO:0000250|UniProtKB:Q9R1L5}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9R1L5}. Note=Also localized in the soma of neurons. Observed as punctate clusters in the processes of interneurons and along the cell body periphery. Colocalizes with syntrophins at the cell membrane. {ECO:0000250|UniProtKB:Q9R1L5}. |
| Mouse PG classification | NA |
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