| Gene Information | |
|---|---|
| Gene Name | SEPT7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Septin-7 (CDC10 protein homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16181 |
| Gene Card | SEPTIN7 |
| Uniprot ID | Q16181 |
| Pfam | PF00735 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15915442}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QAG (X-ray 4.00A ) 3T5D (X-ray 3.30A ) 3TW4 (X-ray 3.35A ) 6N0B (X-ray 1.74A ) 6N12 (X-ray 2.23A ) 6UQQ (X-ray 2.75A ) 7M6J (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18460473}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:18460473}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18460473}. Cleavage furrow {ECO:0000269|PubMed:18460473}. Midbody {ECO:0000269|PubMed:18460473}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:25588830}. Note=Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers (By similarity). Found in the sperm annulus (PubMed:25588830). {ECO:0000250, ECO:0000269|PubMed:25588830}. |
| Mouse PG classification | NA |
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