| Gene Information | |
|---|---|
| Gene Name | REEP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 201 |
| Protein Names | Receptor expression-enhancing protein 1 (Spastic paraplegia 31 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000068615 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H902 |
| Gene Card | REEP1 |
| Uniprot ID | Q9H902 |
| Pfam | PF03134 |
| In ASD | no |
| Allosteric Prediction | no (-1.286144242) |
| Ortholog in Animals | Alpaca_ REEP1 ( ortholog_one2one ) Dog_ REEP1 ( ortholog_one2one ) GuineaPig_ REEP1 ( ortholog_one2one ) Macaque_ REEP1 ( ortholog_one2one ) Mouse_ Reep1 ( ortholog_one2one ) Pig_ REEP1 ( ortholog_one2one ) Rat_ Reep1 ( ortholog_one2one ) Rabbit_ REEP1 ( ortholog_one2one ) |
| Ohnologs | REEP2, REEP3, REEP4 |
| Paralogs | REEP3, REEP5, REEP6, REEP2, REEP4 |
| Tissue | NA |
| Tissue Specificity | Expressed in circumvallate papillae and testis. {ECO:0000269|PubMed:16720576}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1060503496 rs121918262 rs1060503493 |
| Subcellular location [CC] | Membrane {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:16826527}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum {ECO:0000269|PubMed:20200447}. Note=Localizes to endoplasmic reticulum tubular network. {ECO:0000269|PubMed:20200447}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |