| Gene Information | |
|---|---|
| Gene Name | SEPHS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 392 |
| Protein Names | Selenide, water dikinase 1 (EC 2.7.9.3) (Selenium donor protein 1) (Selenophosphate synthase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000086475 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P49903 |
| Gene Card | SEPHS1 |
| Uniprot ID | P49903 |
| Pfam | PF00586; PF02769 |
| In ASD | no |
| Allosteric Prediction | no (-1.122696759) |
| Ortholog in Animals | Dog_ SEPHS1 ( ortholog_one2many ) GuineaPig_ SEPHS1 ( ortholog_one2one ) Macaque_ SEPHS1 ( ortholog_one2one ) Mouse_ Sephs1 ( ortholog_one2one ) Pig_ SEPHS1 ( ortholog_one2one ) Rat_ Sephs1 ( ortholog_one2one ) Rabbit_ SEPHS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SEPHS2 |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases. {ECO:0000269|PubMed:20471958}.; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases. {ECO:0000269|PubMed:20471958}.; [Isoform 3]: Gradually expressed during the cell cycle until S phase and then decreases. {ECO:0000269|PubMed:20471958}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3FD5 (X-ray 1.90A ) 3FD6 (X-ray 1.95A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:20471958}; Peripheral membrane protein {ECO:0000305}. Nucleus membrane {ECO:0000269|PubMed:20471958}; Peripheral membrane protein {ECO:0000305}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:20471958}.; [Isoform 3]: Cytoplasm {ECO:0000269|PubMed:20471958}.; [Isoform 4]: Cytoplasm {ECO:0000269|PubMed:20471958}. |
| Mouse PG classification | NA |
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