| Gene Information | |
|---|---|
| Gene Name | ACY3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 319 |
| Protein Names | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) (EC 3.5.1.114) (Acylase III) (Aminoacylase-3) (ACY-3) (Aspartoacylase-2) (Hepatitis C virus core-binding protein 1) (HCBP1) (HCV core-binding protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000132744 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96HD9 |
| Gene Card | ACY3 |
| Uniprot ID | Q96HD9 |
| Pfam | PF04952 |
| In ASD | no |
| Allosteric Prediction | no (-0.203570757) |
| Ortholog in Animals | Alpaca_ ACY3 ( ortholog_one2one ) GuineaPig_ ACY3 ( ortholog_one2one ) Macaque_ ACY3 ( ortholog_one2one ) Mouse_ Acy3 ( ortholog_one2one ) Rat_ Acy3 ( ortholog_one2one ) |
| Ohnologs | ASPA |
| Paralogs | ASPA |
| Tissue | kidney, small.intestine, cortex.of.kidney, liver, small.intestine.Peyers.patch |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs948445 rs2290959 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:19486448}; Peripheral membrane protein {ECO:0000269|PubMed:19486448}. Cytoplasm {ECO:0000269|PubMed:19486448}. Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm. |
| Mouse PG classification | NA |
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