| Gene Information | |
|---|---|
| Gene Name | SENP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 589 |
| Protein Names | Sentrin-specific protease 2 (EC 3.4.22.-) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000163904 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HC62 |
| Gene Card | SENP2 |
| Uniprot ID | Q9HC62 |
| Pfam | PF02902 |
| In ASD | no |
| Allosteric Prediction | no (-0.289339054) |
| Ortholog in Animals | Alpaca_ SENP2 ( ortholog_one2one ) Dog_ SENP2 ( ortholog_one2one ) GuineaPig_ SENP2 ( ortholog_one2one ) Macaque_ SENP2 ( ortholog_one2one ) Mouse_ Senp2 ( ortholog_one2one ) Pig_ SENP2 ( ortholog_one2one ) Rat_ Senp2 ( ortholog_one2one ) Rabbit_ SENP2 ( ortholog_one2one ) |
| Ohnologs | SENP1 |
| Paralogs | SENP5, SENP3, SENP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TGZ (X-ray 2.80A ) 1TH0 (X-ray 2.20A ) 2IO0 (X-ray 2.30A ) 2IO1 (X-ray 2.60A ) 2IO2 (X-ray 2.90A ) 2IO3 (X-ray 3.20A ) 3ZO5 (X-ray 2.15A ) 5AEK (X-ray 3.00A ) |
| DBSNP | rs6762208 |
| Subcellular location [CC] | Nucleus, nuclear pore complex {ECO:0000269|PubMed:12192048}. Nucleus membrane {ECO:0000269|PubMed:12192048}; Peripheral membrane protein {ECO:0000269|PubMed:12192048}; Nucleoplasmic side {ECO:0000269|PubMed:12192048}. Cytoplasm {ECO:0000269|PubMed:16738331}. Note=Shuttles between cytoplasm and nucleus. {ECO:0000269|PubMed:16738331}. |
| Mouse PG classification | NA |
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