Gene Information
Gene NameSEN2
OrganismHomo sapiens (Human)
Gene Length465
Protein NamestRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8NCE0
Gene CardTSEN2
Uniprot IDQ8NCE0
PfamPF01974; PF02778
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIsoform 1 and isoform 2 are widely expressed at very low level. {ECO:0000269|PubMed:15109492}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs12495784  rs33955793  rs113994149 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:15109492}. Nucleus, nucleolus {ECO:0000269|PubMed:15109492}. Note=May be transiently localized in the nucleolus.
Mouse PG classificationNA
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