| Gene Information | |
|---|---|
| Gene Name | CHMP2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 222 |
| Protein Names | Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000130724 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43633 |
| Gene Card | CHMP2A |
| Uniprot ID | O43633 |
| Pfam | PF03357 |
| In ASD | no |
| Allosteric Prediction | no (-0.176127991) |
| Ortholog in Animals | Alpaca_ CHMP2A ( ortholog_one2one ) Dog_ CHMP2A ( ortholog_one2one ) GuineaPig_ CHMP2A ( ortholog_one2one ) Macaque_ CHMP2A ( ortholog_one2one ) Mouse_ Chmp2a ( ortholog_one2one ) Pig_ CHMP2A ( ortholog_one2one ) Rat_ Chmp2a ( ortholog_one2one ) Rabbit_ CHMP2A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHMP2B, CHMP3, CHMP1B, CHMP1A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.173451(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Late endosome membrane {ECO:0000269|PubMed:16730941, ECO:0000269|PubMed:17853893}; Peripheral membrane protein {ECO:0000269|PubMed:16730941, ECO:0000269|PubMed:17853893}; Cytoplasmic side {ECO:0000269|PubMed:16730941, ECO:0000269|PubMed:17853893}. Nucleus envelope {ECO:0000269|PubMed:28242692}. Note=Localizes to the midbody of dividing cells. Localized in two distinct rings on either side of the Fleming body. Localizes to the reforming nuclear envelope on chromatin disks during late anaphase (PubMed:28242692). {ECO:0000269|PubMed:28242692}. |
| Mouse PG classification | NA |
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