Gene Information
Gene NameTSGA10
OrganismHomo sapiens (Human)
Gene Length698
Protein NamesTestis-specific gene 10 protein (Testis development protein NYD-SP7)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000135951 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ9BZW7
Gene CardTSGA10
Uniprot IDQ9BZW7
PfamNA
In ASDno
Allosteric Predictionno (-1.514104737)
Ortholog in AnimalsAlpaca_ TSGA10 ( ortholog_one2one )
Dog_ TSGA10 ( ortholog_one2one )
GuineaPig_ TSGA10 ( ortholog_one2one )
Macaque_ TSGA10 ( ortholog_one2one )
Mouse_ Tsga10 ( ortholog_one2one )
Pig_ TSGA10 ( ortholog_one2one )
Rat_ Tsga10 ( ortholog_one2one )
Rabbit_ TSGA10 ( ortholog_one2one )
OhnologsCEP135
ParalogsCEP135, CROCC2, CROCC, CEP250
Tissuetestis
Tissue SpecificityExpressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816). {ECO:0000269|PubMed:11179690, ECO:0000269|PubMed:14585816, ECO:0000269|PubMed:28905369}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000250|UniProtKB:Q9Z220}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:28905369}. Note=In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). {ECO:0000250|UniProtKB:Q9Z220, ECO:0000269|PubMed:28905369}.
Mouse PG classificationNA
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