| Gene Information | |
|---|---|
| Gene Name | VAMP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 118 |
| Protein Names | Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1) |
| Target Name | vesicle-associated membrane protein 1 |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000139190 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P23763 |
| Gene Card | VAMP1 |
| Uniprot ID | P23763 |
| Pfam | PF00957 |
| In ASD | no |
| Allosteric Prediction | no (-1.070081537) |
| Ortholog in Animals | Alpaca_ VAMP1 ( ortholog_one2one ) Dog_ VAMP1 ( ortholog_one2one ) GuineaPig_ VAMP1 ( ortholog_one2one ) Macaque_ VAMP1 ( ortholog_one2one ) Mouse_ Vamp1 ( ortholog_one2one ) Rat_ Vamp1 ( ortholog_one2one ) Rabbit_ VAMP1 ( ortholog_one2one ) |
| Ohnologs | VAMP3 |
| Paralogs | VAMP8, VAMP2, SEC22A, VAMP7, VAMP3, VAMP4, SEC22C, VAMP5, SEC22B, YKT6 |
| Tissue | occipital.cortex, occipital.lobe, substantia.nigra |
| Tissue Specificity | Nervous system, skeletal muscle and adipose tissue. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.057143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs754046104 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Synapse, synaptosome {ECO:0000250}.; [Isoform 2]: Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Synapse, synaptosome {ECO:0000250}.; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein {ECO:0000269|PubMed:9658161}. |
| Mouse PG classification | NA |
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