| Gene Information | |
|---|---|
| Gene Name | GPR20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | G-protein coupled receptor 20 |
| Target Name | g-protein coupled receptor 20 |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000204882 ) 3 ( ENSG00000275181 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99678 |
| Gene Card | GPR20 |
| Uniprot ID | Q99678 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.457228683) |
| Ortholog in Animals | Alpaca_ GPR20 ( ortholog_one2one ) Dog_ GPR20 ( ortholog_one2one ) GuineaPig_ GPR20 ( ortholog_one2one ) Macaque_ GPR20 ( ortholog_one2one ) Mouse_ Gpr20 ( ortholog_one2one ) Pig_ GPR20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | F2RL2, P2RY8, F2RL1, F2R, F2RL3, GPR18, GPR65, CYSLTR2, GPR17, GPR4, CYSLTR1, LPAR4, LPAR6, P2RY10, GPR35, GPR55 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus. {ECO:0000269|PubMed:18347022}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10875472 rs36092215 rs34591516 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18347022}; Multi-pass membrane protein {ECO:0000269|PubMed:18347022}. |
| Mouse PG classification | NA |
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