Gene Information
Gene NameVPS35L
OrganismHomo sapiens (Human)
Gene Length963
Protein NamesVPS35 endosomal protein-sorting factor-like (Esophageal cancer-associated protein)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000103544 )
Evolutionary StageEukaryota
AlphaFoldDBQ7Z3J2
Gene CardVPS35L
Uniprot IDQ7Z3J2
PfamNA
In ASDno
Allosteric Predictionno (-1.668546401)
Ortholog in AnimalsAlpaca_ VPS35L ( ortholog_one2one )
Dog_ VPS35L ( ortholog_one2one )
GuineaPig_ VPS35L ( ortholog_one2one )
Macaque_ VPS35L ( ortholog_one2one )
Mouse_ Vps35l ( ortholog_one2one )
Pig_ VPS35L ( ortholog_one2one )
Rat_ Vps35l ( ortholog_one2one )
Rabbit_ VPS35L ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17854969  rs7206637  rs17854970  rs747119819 
Subcellular location [CC]Membrane {ECO:0000255};
Single-pass membrane protein {ECO:0000255}. Endosome {ECO:0000269|PubMed:25355947, ECO:0000269|PubMed:28892079}. Note=Endosome location is dependent of the association with the CCC and WASH complexes. {ECO:0000269|PubMed:28892079}.
Mouse PG classificationNA
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