| Gene Information | |
|---|---|
| Gene Name | SLITRK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 977 |
| Protein Names | SLIT and NTRK-like protein 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000121871 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O94933 |
| Gene Card | SLITRK3 |
| Uniprot ID | O94933 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-1.181055419) |
| Ortholog in Animals | Alpaca_ SLITRK3 ( ortholog_one2one ) Dog_ SLITRK3 ( ortholog_one2one ) GuineaPig_ SLITRK3 ( ortholog_one2one ) Macaque_ SLITRK3 ( ortholog_one2one ) Mouse_ Slitrk3 ( ortholog_one2one ) Pig_ SLITRK3 ( ortholog_one2one ) Rat_ Slitrk3 ( ortholog_one2one ) Rabbit_ SLITRK3 ( ortholog_one2one ) |
| Ohnologs | SLITRK5, SLITRK1, SLITRK4, SLITRK6, SLITRK2 |
| Paralogs | TLR9, LRRC70, LRFN2, LRFN5, LRFN4, GP5, SLITRK2, LINGO1, TPBGL, SLITRK6, LRFN1, LRRN1, SLITRK1, LRTM2, SLIT3, LRRN2, LRRN3, SLIT2, LRRC38, SLITRK4, LINGO2, SLIT1, SLITRK5, LRRC55, LRFN3 |
| Tissue | NA |
| Tissue Specificity | Expressed in the occipital lobe of the cerebral cortex of the brain. Expressed at higher levels in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors. {ECO:0000269|PubMed:14557068}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3828419 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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