| Gene Information | |
|---|---|
| Gene Name | AP1B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 949 |
| Protein Names | AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000100280 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q10567 |
| Gene Card | AP1B1 |
| Uniprot ID | Q10567 |
| Pfam | PF01602; PF02883; PF09066 |
| In ASD | no |
| Allosteric Prediction | no (-0.441505626) |
| Ortholog in Animals | Alpaca_ AP1B1 ( ortholog_one2one ) Dog_ AP1B1 ( ortholog_one2one ) GuineaPig_ AP1B1 ( ortholog_one2one ) Macaque_ AP1B1 ( ortholog_one2one ) Mouse_ Ap1b1 ( ortholog_one2one ) Pig_ AP1B1 ( ortholog_one2one ) Rat_ Ap1b1 ( ortholog_one2one ) Rabbit_ AP1B1 ( ortholog_one2one ) |
| Ohnologs | AP2B1 |
| Paralogs | AP4B1, AP2B1, AP3B2, AP3B1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | 0.021380(Chimpanzee);0.158233(Mouse);NULL(Rat);0.029268(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 4HMY (X-ray 7.00A ) 4P6Z (X-ray 3.00A ) 6CM9 (EM 3.73A ) 6CRI (EM 6.80A ) 6D83 (EM 4.27A ) 6D84 (EM 6.72A ) 6DFF (EM 3.90A ) |
| DBSNP | rs2857465 |
| Subcellular location [CC] | Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
| Mouse PG classification | NA |
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