| Gene Information | |
|---|---|
| Gene Name | SNRPD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 126 |
| Protein Names | Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100028 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P62318 |
| Gene Card | SNRPD3 |
| Uniprot ID | P62318 |
| Pfam | PF01423 |
| In ASD | no |
| Allosteric Prediction | no (-0.985314892) |
| Ortholog in Animals | Alpaca_ SNRPD3 ( ortholog_one2one ) Dog_ SNRPD3 ( ortholog_one2one ) GuineaPig_ SNRPD3 ( ortholog_one2one ) Macaque_ SNRPD3 ( ortholog_one2one ) Mouse_ Snrpd3 ( ortholog_one2one ) Rat_ AABR07042875.1 ( ortholog_one2one ) Rabbit_ SNRPD3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LSM4, SNRPD1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.330416(Chimpanzee);0.118635(Mouse);NULL(Rat);0.153527(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1D3B (X-ray 2.00A ) 3CW1 (X-ray 5.49A ) 3JCR (EM 7.00A ) 3PGW (X-ray 4.40A ) 3VRI (X-ray 1.60A ) 4PJO (X-ray 3.30A ) 4WZJ (X-ray 3.60A ) 5MQF (EM 5.90A ) 5O9Z (EM 4.50A ) 5XJC (EM 3.60A ) 5YZG (EM 4.10A ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 5Z58 (EM 4.90A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6FF7 (EM 4.50A ) 6ICZ (EM 3.00A ) 6ID0 (EM 2.90A ) 6ID1 (EM 2.86A ) 6QDV (EM 3.30A ) 6QW6 (EM 2.92A ) 6QX9 (EM 3.28A ) 6V4X (EM 3.20A ) 6Y53 (EM 7.10A ) 6Y5Q (EM 7.10A ) 7A5P (EM 5.00A ) 7ABG (EM 7.80A ) 7ABI (EM 8.00A ) 7B0Y (EM 3.60A ) 7DVQ (EM 2.89A ) 7EVO (EM 2.50A ) 7W59 (EM 3.60A ) 7W5A (EM 3.60A ) 7W5B (EM 4.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:11574479, ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:28781166}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000305}. |
| Mouse PG classification | NA |
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