| Gene Information | |
|---|---|
| Gene Name | CABP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000157782 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NZU7 |
| Gene Card | CABP1 |
| Uniprot ID | Q9NZU7 |
| Pfam | PF13499 |
| In ASD | no |
| Allosteric Prediction | no (-0.45599872) |
| Ortholog in Animals | Alpaca_ CABP1 ( ortholog_one2one ) Dog_ CABP1 ( ortholog_one2one ) Macaque_ CABP1 ( ortholog_one2one ) Mouse_ Cabp1 ( ortholog_one2one ) Pig_ CABP1 ( ortholog_one2one ) Rat_ Cabp1 ( ortholog_one2one ) |
| Ohnologs | CABP2, CABP4 |
| Paralogs | CABP2, EFCAB7, CALN1, EFCAB3, CABP7, CETN3, CALM1, CALML3, CALM3, CALM2, CALML5, CETN1, CALML6, CABP4, CALML4, CABP5, CETN2, EFCAB12, EFCAB2, EFCAB9 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2K7B (NMR - ) 2K7C (NMR - ) 2K7D (NMR - ) 2LAN (NMR - ) 2LAP (NMR - ) 3OX5 (X-ray 2.90A ) 3OX6 (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10625670}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:14685260}. Cell membrane {ECO:0000269|PubMed:10625670, ECO:0000269|PubMed:14570872, ECO:0000269|PubMed:14685260}; Lipid-anchor; Cytoplasmic side. Golgi apparatus {ECO:0000269|PubMed:14570872, ECO:0000269|PubMed:14685260}. Postsynaptic density {ECO:0000305}. Note=L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane. {ECO:0000269|PubMed:10625670}.; [Isoform L-CaBP1]: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10625670}. Note=L-CaBP1 is associated most likely with the cytoskeletal structures. {ECO:0000269|PubMed:10625670}.; [Isoform S-CaBP1]: Cytoplasm, cell cortex. Cell membrane {ECO:0000305|PubMed:10625670}; Lipid-anchor {ECO:0000305}. Note=S-CaBP1 is localized at or near the plasma membrane. |
| Mouse PG classification | NA |
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