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Gene Information
Gene Name
HBA2
Organism
Homo sapiens (Human)
Gene Length
142
Protein Names
Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin]
Target Name
hemoglobin
Target Type
Successful target
Gene Age
645 ( ENSG00000188536 )
Evolutionary Stage
Vertebrata
AlphaFoldDB
P69905
Gene Card
HBA1;HBA2
Uniprot ID
P69905
Pfam
PF00042
In ASD
yes
Allosteric Prediction
NA
Ortholog in Animals
Alpaca_ HBA2 ( ortholog_many2many )
GuineaPig_ GLNC1 ( ortholog_one2many )
Mouse_ Hba-a1 ( ortholog_many2many )
Mouse_ Hba-a2 ( ortholog_many2many )
Rat_ Hba-a2 ( ortholog_many2many )
Rat_ Hba-a3 ( ortholog_many2many )
Ohnologs
NA
Paralogs
HBA1, CYGB, HBG2, HBG1, HBQ1, HBE1, HBD, HBB, HBM, HBZ, MB
Tissue
spleen
Tissue Specificity
Red blood cells.
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1A00
(X-ray
2.00A
)
1A01
(X-ray
1.80A
)
1A0U
(X-ray
2.14A
)
1A0Z
(X-ray
2.00A
)
1A3N
(X-ray
1.80A
)
1A3O
(X-ray
1.80A
)
1A9W
(X-ray
2.90A
)
1ABW
(X-ray
2.00A
)
1ABY
(X-ray
2.60A
)
1AJ9
(X-ray
2.20A
)
1B86
(X-ray
2.50A
)
1BAB
(X-ray
1.50A
)
1BBB
(X-ray
1.70A
)
1BIJ
(X-ray
2.30A
)
1BUW
(X-ray
1.90A
)
1BZ0
(X-ray
1.50A
)
1BZ1
(X-ray
1.59A
)
1BZZ
(X-ray
1.59A
)
1C7B
(X-ray
1.80A
)
1C7C
(X-ray
1.80A
)
1C7D
(X-ray
1.80A
)
1CLS
(X-ray
1.90A
)
1CMY
(X-ray
3.00A
)
1COH
(X-ray
2.90A
)
1DKE
(X-ray
2.10A
)
1DXT
(X-ray
1.70A
)
1DXU
(X-ray
1.70A
)
1DXV
(X-ray
1.70A
)
1FDH
(X-ray
2.50A
)
1FN3
(X-ray
2.48A
)
1G9V
(X-ray
1.85A
)
1GBU
(X-ray
1.80A
)
1GBV
(X-ray
2.00A
)
1GLI
(X-ray
2.50A
)
1GZX
(X-ray
2.10A
)
1HAB
(X-ray
2.30A
)
1HAC
(X-ray
2.60A
)
1HBA
(X-ray
2.10A
)
1HBB
(X-ray
1.90A
)
1HBS
(X-ray
3.00A
)
1HCO
(X-ray
2.70A
)
1HDB
(X-ray
2.20A
)
1HGA
(X-ray
2.10A
)
1HGB
(X-ray
2.10A
)
1HGC
(X-ray
2.10A
)
1HHO
(X-ray
2.10A
)
1IRD
(X-ray
1.25A
)
1J3Y
(X-ray
1.55A
)
1J3Z
(X-ray
1.60A
)
1J40
(X-ray
1.45A
)
1J41
(X-ray
1.45A
)
1J7S
(X-ray
2.20A
)
1J7W
(X-ray
2.00A
)
1J7Y
(X-ray
1.70A
)
1JY7
(X-ray
3.20A
)
1K0Y
(X-ray
1.87A
)
1K1K
(X-ray
2.00A
)
1KD2
(X-ray
1.87A
)
1LFL
(X-ray
2.70A
)
1LFQ
(X-ray
2.60A
)
1LFT
(X-ray
2.60A
)
1LFV
(X-ray
2.80A
)
1LFY
(X-ray
3.30A
)
1LFZ
(X-ray
3.10A
)
1LJW
(X-ray
2.16A
)
1M9P
(X-ray
2.10A
)
1MKO
(X-ray
2.18A
)
1NEJ
(X-ray
2.10A
)
1NIH
(X-ray
2.60A
)
1NQP
(X-ray
1.73A
)
1O1I
(X-ray
2.30A
)
1O1J
(X-ray
1.90A
)
1O1K
(X-ray
2.00A
)
1O1L
(X-ray
1.80A
)
1O1M
(X-ray
1.85A
)
1O1N
(X-ray
1.80A
)
1O1O
(X-ray
1.80A
)
1O1P
(X-ray
1.80A
)
1QI8
(X-ray
1.80A
)
1QSH
(X-ray
1.70A
)
1QSI
(X-ray
1.70A
)
1QXD
(X-ray
2.25A
)
1QXE
(X-ray
1.85A
)
1R1X
(X-ray
2.15A
)
1R1Y
(X-ray
1.80A
)
1RPS
(X-ray
2.11A
)
1RQ3
(X-ray
1.91A
)
1RQ4
(X-ray
2.11A
)
1RQA
(X-ray
2.11A
)
1RVW
(X-ray
2.50A
)
1SDK
(X-ray
1.80A
)
1SDL
(X-ray
1.80A
)
1SHR
(X-ray
1.88A
)
1SI4
(X-ray
2.20A
)
1THB
(X-ray
1.50A
)
1UIW
(X-ray
1.50A
)
1VWT
(X-ray
1.90A
)
1XXT
(X-ray
1.91A
)
1XY0
(X-ray
1.99A
)
1XYE
(X-ray
2.13A
)
1XZ2
(X-ray
1.90A
)
1XZ4
(X-ray
2.00A
)
1XZ5
(X-ray
2.11A
)
1XZ7
(X-ray
1.90A
)
1XZU
(X-ray
2.16A
)
1XZV
(X-ray
2.11A
)
1Y01
(X-ray
2.80A
)
1Y09
(X-ray
2.25A
)
1Y0A
(X-ray
2.22A
)
1Y0C
(X-ray
2.30A
)
1Y0D
(X-ray
2.10A
)
1Y0T
(X-ray
2.14A
)
1Y0W
(X-ray
2.14A
)
1Y22
(X-ray
2.16A
)
1Y2Z
(X-ray
2.07A
)
1Y31
(X-ray
2.13A
)
1Y35
(X-ray
2.12A
)
1Y45
(X-ray
2.00A
)
1Y46
(X-ray
2.22A
)
1Y4B
(X-ray
2.10A
)
1Y4F
(X-ray
2.00A
)
1Y4G
(X-ray
1.91A
)
1Y4P
(X-ray
1.98A
)
1Y4Q
(X-ray
2.11A
)
1Y4R
(X-ray
2.22A
)
1Y4V
(X-ray
1.84A
)
1Y5F
(X-ray
2.14A
)
1Y5J
(X-ray
2.03A
)
1Y5K
(X-ray
2.20A
)
1Y7C
(X-ray
2.10A
)
1Y7D
(X-ray
1.90A
)
1Y7G
(X-ray
2.10A
)
1Y7Z
(X-ray
1.98A
)
1Y83
(X-ray
1.90A
)
1Y85
(X-ray
2.13A
)
1Y8W
(X-ray
2.90A
)
1YDZ
(X-ray
3.30A
)
1YE0
(X-ray
2.50A
)
1YE1
(X-ray
4.50A
)
1YE2
(X-ray
1.80A
)
1YEN
(X-ray
2.80A
)
1YEO
(X-ray
2.22A
)
1YEQ
(X-ray
2.75A
)
1YEU
(X-ray
2.12A
)
1YEV
(X-ray
2.11A
)
1YFF
(X-ray
2.40A
)
1YG5
(X-ray
2.70A
)
1YGD
(X-ray
2.73A
)
1YGF
(X-ray
2.70A
)
1YH9
(X-ray
2.20A
)
1YHE
(X-ray
2.10A
)
1YHR
(X-ray
2.60A
)
1YIE
(X-ray
2.40A
)
1YIH
(X-ray
2.00A
)
1YVQ
(X-ray
1.80A
)
1YVT
(X-ray
1.80A
)
1YZI
(X-ray
2.07A
)
1Z8U
(X-ray
2.40A
)
2D5Z
(X-ray
1.45A
)
2D60
(X-ray
1.70A
)
2DN1
(X-ray
1.25A
)
2DN2
(X-ray
1.25A
)
2DN3
(X-ray
1.25A
)
2DXM
(Neutron
2.10A
)
2H35
(NMR
-
)
2HBC
(X-ray
2.10A
)
2HBD
(X-ray
2.20A
)
2HBE
(X-ray
2.00A
)
2HBF
(X-ray
2.20A
)
2HBS
(X-ray
2.05A
)
2HCO
(X-ray
2.70A
)
2HHB
(X-ray
1.74A
)
2HHD
(X-ray
2.20A
)
2HHE
(X-ray
2.20A
)
2M6Z
(NMR
-
)
2W6V
(X-ray
1.80A
)
2W72
(X-ray
1.07A
)
2YRS
(X-ray
2.30A
)
3B75
(X-ray
2.30A
)
3D17
(X-ray
2.80A
)
3D7O
(X-ray
1.80A
)
3DUT
(X-ray
1.55A
)
3HHB
(X-ray
1.74A
)
3HXN
(X-ray
2.00A
)
3IA3
(X-ray
3.20A
)
3IC0
(X-ray
1.80A
)
3IC2
(X-ray
2.40A
)
3KMF
(Neutron
2.00A
)
3NL7
(X-ray
1.80A
)
3NMM
(X-ray
1.60A
)
3ODQ
(X-ray
3.10A
)
3ONZ
(X-ray
2.09A
)
3OO4
(X-ray
1.90A
)
3OO5
(X-ray
2.10A
)
3OVU
(X-ray
2.83A
)
3P5Q
(X-ray
2.00A
)
3QJB
(X-ray
1.80A
)
3QJC
(X-ray
2.00A
)
3QJD
(X-ray
1.56A
)
3QJE
(X-ray
1.80A
)
3R5I
(X-ray
2.20A
)
3S48
(X-ray
3.05A
)
3S65
(X-ray
1.80A
)
3S66
(X-ray
1.40A
)
3SZK
(X-ray
3.01A
)
3WCP
(X-ray
1.94A
)
3WHM
(X-ray
1.85A
)
4FC3
(X-ray
2.26A
)
4HHB
(X-ray
1.74A
)
4IJ2
(X-ray
4.24A
)
4L7Y
(X-ray
1.80A
)
4M4A
(X-ray
2.05A
)
4M4B
(X-ray
2.00A
)
4MQC
(X-ray
2.20A
)
4MQG
(X-ray
1.68A
)
4MQH
(X-ray
2.50A
)
4MQI
(X-ray
1.92A
)
4MQJ
(X-ray
1.80A
)
4MQK
(X-ray
2.24A
)
4N7N
(X-ray
2.75A
)
4N7O
(X-ray
2.50A
)
4N7P
(X-ray
2.81A
)
4N8T
(X-ray
1.90A
)
4NI0
(X-ray
2.15A
)
4NI1
(X-ray
1.90A
)
4ROL
(X-ray
1.70A
)
4ROM
(X-ray
1.90A
)
4WJG
(X-ray
3.10A
)
4X0L
(X-ray
2.05A
)
4XS0
(X-ray
2.55A
)
5E29
(X-ray
1.85A
)
5E6E
(X-ray
1.76A
)
5E83
(X-ray
1.80A
)
5EE4
(X-ray
2.30A
)
5HU6
(X-ray
2.90A
)
5HY8
(X-ray
2.30A
)
5JDO
(X-ray
3.20A
)
5KDQ
(X-ray
2.15A
)
5KSI
(X-ray
1.80A
)
5KSJ
(X-ray
2.40A
)
5NI1
(EM
3.20A
)
5SW7
(X-ray
1.85A
)
5U3I
(X-ray
1.95A
)
5UCU
(X-ray
1.80A
)
5UFJ
(X-ray
2.05A
)
5URC
(X-ray
1.85A
)
5VMM
(X-ray
3.60A
)
5WOG
(X-ray
1.54A
)
5WOH
(X-ray
1.58A
)
5X2R
(X-ray
2.70A
)
5X2S
(X-ray
2.39A
)
5X2T
(X-ray
2.64A
)
5X2U
(X-ray
2.53A
)
6BB5
(X-ray
2.28A
)
6BNR
(X-ray
1.95A
)
6BWP
(X-ray
1.70A
)
6BWU
(X-ray
2.00A
)
6DI4
(X-ray
1.90A
)
6HAL
(X-ray
2.20A
)
6HBW
(X-ray
2.00A
)
6HK2
(X-ray
1.55A
)
6KA9
(X-ray
1.40A
)
6KAE
(X-ray
1.45A
)
6KAH
(X-ray
1.45A
)
6KAI
(X-ray
1.45A
)
6KAO
(X-ray
1.40A
)
6KAP
(X-ray
1.45A
)
6KAQ
(X-ray
1.50A
)
6KAR
(X-ray
1.60A
)
6KAS
(X-ray
1.65A
)
6KAT
(X-ray
1.70A
)
6KAU
(X-ray
1.60A
)
6KAV
(X-ray
1.70A
)
6KYE
(X-ray
2.28A
)
6L5V
(X-ray
1.45A
)
6L5W
(X-ray
1.50A
)
6L5X
(X-ray
1.65A
)
6L5Y
(X-ray
1.65A
)
6LCW
(X-ray
1.40A
)
6LCX
(X-ray
1.40A
)
6NBC
(EM
2.80A
)
6NBD
(EM
3.20A
)
6NQ5
(X-ray
1.85A
)
6TB2
(X-ray
2.90A
)
6XD9
(X-ray
2.10A
)
6XDT
(X-ray
1.90A
)
6XE7
(X-ray
2.00A
)
7AET
(X-ray
2.53A
)
7AEU
(X-ray
2.54A
)
7AEV
(X-ray
2.77A
)
7CUE
(X-ray
2.75A
)
7DY3
(X-ray
1.40A
)
7DY4
(X-ray
1.30A
)
7JJQ
(X-ray
2.15A
)
7JXZ
(X-ray
2.23A
)
7JY0
(X-ray
1.63A
)
7JY1
(X-ray
1.59A
)
7JY3
(X-ray
1.48A
)
7K4M
(X-ray
2.50A
)
7PCF
(EM
5.82A
)
7PCH
(EM
2.89A
)
7PCQ
(EM
3.62A
)
7UD7
(X-ray
1.80A
)
7UD8
(X-ray
1.80A
)
7UF6
(X-ray
2.00A
)
7UF7
(X-ray
2.00A
)
7VDE
(EM
3.20A
)
DBSNP
rs33981821
rs36030576
rs34090856
rs34751764
rs33986902
rs281864805
rs33961916
rs281864805
rs281864806
rs34817956
rs281860608
rs33938574
rs35615982
rs35331909
rs33964317
rs35816645
rs35210126
rs281860619
rs35993097
rs34504387
rs35628685
rs41525149
rs33943087
rs11548605
rs34324664
rs34608326
rs33939421
rs281864819
rs281864821
rs281864822
rs281864822
rs281865556
rs281864823
rs281864823
rs111033605
rs281864543
rs111033606
rs281864825
rs281864826
rs281864828
rs281860623
rs41491146
rs281864830
rs281864830
rs281860624
rs281864831
rs281864833
rs281864833
rs281864834
rs281864834
rs41392146
rs41518249
rs281864835
rs281864836
rs281864837
rs281864838
rs281864839
rs281864841
rs281864841
rs281864843
rs41378349
rs281864845
rs28928878
rs281864846
rs111033598
rs33985574
rs281865558
rs41515649
rs34502246
rs33984024
rs1060339
rs281864853
rs281864853
rs281864854
rs281864856
rs33921047
rs281864857
rs33991223
rs281864858
rs33969953
rs33969953
rs281864861
rs111033602
rs281860607
rs281860603
rs281864863
rs281864864
rs281864865
rs281860612
rs41331747
rs281864777
rs281864866
rs281864868
rs281864867
rs35239527
rs281864873
rs281864494
rs281864874
rs281864875
rs281864876
rs281864879
rs281864878
rs281864881
rs281864881
rs41338947
rs281864882
rs41344646
rs63750752
rs63750073
rs41479844
rs28928889
rs281864885
rs281860618
rs267607269
rs267607269
rs281864887
rs281864888
rs281864946
rs36075744
rs35187567
rs41479347
rs41397847
rs41397847
rs33957766
rs33957766
rs33933481
rs33972894
rs281864889
rs41528545
rs41529844
rs63751417
rs55948437
rs63749809
rs41364652
rs41469945
rs41469945
rs63750801
rs41361546
rs56348461
rs55870409
rs63750134
rs33935328
rs33935328
rs33935328
Subcellular location [CC]
NA
Mouse PG classification
NA
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