| Gene Information | |
|---|---|
| Gene Name | GATAD2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 633 |
| Protein Names | Transcriptional repressor p66-alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000167491 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86YP4 |
| Gene Card | GATAD2A |
| Uniprot ID | Q86YP4 |
| Pfam | PF00320; PF16563 |
| In ASD | no |
| Allosteric Prediction | no (-0.112128331) |
| Ortholog in Animals | Alpaca_ GATAD2A ( ortholog_one2many ) Dog_ GATAD2A ( ortholog_one2one ) GuineaPig_ GATAD2A ( ortholog_one2one ) Macaque_ GATAD2A ( ortholog_one2one ) Mouse_ Gatad2a ( ortholog_one2one ) Pig_ GATAD2A ( ortholog_one2one ) Rat_ Gatad2a ( ortholog_one2one ) Rabbit_ GATAD2A ( ortholog_one2one ) |
| Ohnologs | GATAD2B |
| Paralogs | GATAD2B |
| Tissue | NA |
| Tissue Specificity | Ubiquitous, both in fetal and adult tissues. {ECO:0000269|PubMed:12183469}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.114814(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L2L (NMR - ) |
| DBSNP | rs10426883 rs2288851 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:12183469, ECO:0000269|PubMed:16415179}. Note=Speckled nuclear localization requires both CR1 and CR2 regions. {ECO:0000269|PubMed:16415179}. |
| Mouse PG classification | NA |
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