| Gene Information | |
|---|---|
| Gene Name | SDR8C1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 736 |
| Protein Names | Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P51659 |
| Gene Card | HSD17B4 |
| Uniprot ID | P51659 |
| Pfam | PF00106; PF01575; PF02036 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Present in many tissues with highest concentrations in liver, heart, prostate and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IKT (X-ray 1.75A ) 1S9C (X-ray 3.00A ) 1ZBQ (X-ray 2.71A ) 6Z1W (X-ray 2.48A ) 6Z1X (X-ray 2.09A ) |
| DBSNP | rs137853096 rs28943588 rs25640 rs25640 rs28943589 rs387906825 rs1143650 rs28943590 rs137853097 rs28943591 rs11539471 rs11205 rs15228 rs28943592 rs28943594 |
| Subcellular location [CC] | Peroxisome {ECO:0000305}. |
| Mouse PG classification | NA |
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