| Gene Information | |
|---|---|
| Gene Name | SDE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 451 |
| Protein Names | Splicing regulator SDE2 (Replication stress response regulator SDE2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000143751 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6IQ49 |
| Gene Card | SDE2 |
| Uniprot ID | Q6IQ49 |
| Pfam | PF13019 |
| In ASD | no |
| Allosteric Prediction | no (-1.561490308) |
| Ortholog in Animals | Alpaca_ SDE2 ( ortholog_one2one ) Dog_ SDE2 ( ortholog_one2one ) GuineaPig_ SDE2 ( ortholog_one2one ) Macaque_ SDE2 ( ortholog_one2one ) Mouse_ Sde2 ( ortholog_one2one ) Pig_ SDE2 ( ortholog_one2one ) Rat_ Sde2 ( ortholog_one2one ) Rabbit_ SDE2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SF3A3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed; enriched in brain, lung and liver. {ECO:0000269|PubMed:34365507}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.169224(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6QDV (EM 3.30A ) |
| DBSNP | rs34348128 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:27906959, ECO:0000269|PubMed:34365507}. Cytoplasm {ECO:0000269|PubMed:34365507}. |
| Mouse PG classification | NA |
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