| Gene Information | |
|---|---|
| Gene Name | HACD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 254 |
| Protein Names | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000206527 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6Y1H2 |
| Gene Card | HACD2 |
| Uniprot ID | Q6Y1H2 |
| Pfam | PF04387 |
| In ASD | no |
| Allosteric Prediction | no (-0.839234746) |
| Ortholog in Animals | Alpaca_ HACD2 ( ortholog_one2one ) Dog_ HACD2 ( ortholog_one2one ) GuineaPig_ HACD2 ( ortholog_one2one ) Macaque_ HACD2 ( ortholog_one2one ) Mouse_ Hacd2 ( ortholog_one2one ) Pig_ HACD2 ( ortholog_one2one ) Rat_ Hacd2 ( ortholog_one2one ) Rabbit_ HACD2 ( ortholog_one2one ) |
| Ohnologs | HACD1 |
| Paralogs | HACD1, HACD4, HACD3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis, spleen, prostate, colon and heart, followed by moderate expression in thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle and pancreas. Weakly detected in kidney, placenta, brain and lung. {ECO:0000269|PubMed:15024066}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15024066, ECO:0000269|PubMed:18554506}; Multi-pass membrane protein {ECO:0000269|PubMed:15024066, ECO:0000269|PubMed:18554506}. |
| Mouse PG classification | NA |
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