| Gene Information | |
|---|---|
| Gene Name | SDR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 270 |
| Protein Names | 17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3) (Short chain dehydrogenase/reductase family 47C member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BPX1 |
| Gene Card | HSD17B14 |
| Uniprot ID | Q9BPX1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, placenta, liver and kidney. {ECO:0000269|PubMed:10800688, ECO:0000269|PubMed:17067289}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1YDE (X-ray 2.40A ) 5EN4 (X-ray 1.52A ) 5HS6 (X-ray 2.02A ) 5ICM (X-ray 1.68A ) 5ICS (X-ray 1.52A ) 5JS6 (X-ray 2.00A ) 5JSF (X-ray 1.84A ) 5L7T (X-ray 1.98A ) 5L7W (X-ray 1.76A ) 5L7Y (X-ray 1.91A ) 5O42 (X-ray 1.76A ) 5O43 (X-ray 1.50A ) 5O6O (X-ray 1.45A ) 5O6X (X-ray 1.35A ) 5O6Z (X-ray 1.57A ) 5O72 (X-ray 1.91A ) 5O7C (X-ray 1.60A ) 6EMM (X-ray 2.47A ) 6FFB (X-ray 1.65A ) 6G4L (X-ray 1.44A ) 6GBT (X-ray 2.10A ) 6GTB (X-ray 1.62A ) 6GTU (X-ray 2.25A ) 6H0M (X-ray 1.25A ) 6HNO (X-ray 1.68A ) 6QCK (X-ray 1.68A ) 6ZDE (X-ray 1.87A ) 6ZDI (X-ray 2.13A ) 6ZR6 (X-ray 1.50A ) 6ZRA (X-ray 1.73A ) 6ZT2 (X-ray 1.95A ) |
| DBSNP | rs8110220 rs35299026 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17067289}. |
| Mouse PG classification | NA |
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