| Gene Information | |
|---|---|
| Gene Name | SDHA |
| Organism | Homo sapiens (Human) |
| Gene Length | 664 |
| Protein Names | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) |
| Target Name | succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000073578 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P31040 |
| Gene Card | SDHA |
| Uniprot ID | P31040 |
| Pfam | PF00890; PF02910 |
| In ASD | no |
| Allosteric Prediction | yes (0.897522701) |
| Ortholog in Animals | Alpaca_ SDHA ( ortholog_one2many ) Dog_ SDHA ( ortholog_one2one ) GuineaPig_ SDHA ( ortholog_one2one ) Mouse_ Sdha ( ortholog_one2one ) Pig_ SDHA ( ortholog_one2one ) Rat_ Sdha ( ortholog_one2one ) Rabbit_ SDHA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001596(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6VAX (X-ray 2.59A ) |
| DBSNP | rs1061518 rs34635677 rs1041946 rs1062468 rs1553999752 rs151266052 rs397514541 rs137852767 rs9809219 rs137852768 rs387906780 rs6960 rs6962 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q0QF01}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q0QF01}; Matrix side {ECO:0000250|UniProtKB:Q0QF01}. |
| Mouse PG classification | LPG |
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