| Gene Information | |
|---|---|
| Gene Name | SDF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 362 |
| Protein Names | 45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000078808 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BRK5 |
| Gene Card | SDF4 |
| Uniprot ID | Q9BRK5 |
| Pfam | PF13202; PF13499 |
| In ASD | no |
| Allosteric Prediction | no (-0.301478115) |
| Ortholog in Animals | Alpaca_ SDF4 ( ortholog_one2one ) Dog_ SDF4 ( ortholog_one2one ) GuineaPig_ SDF4 ( ortholog_one2one ) Macaque_ SDF4 ( ortholog_one2one ) Mouse_ Sdf4 ( ortholog_one2one ) Pig_ SDF4 ( ortholog_one2one ) Rat_ Sdf4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RCN2, CALU, RCN3, RCN1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Isoform 5 is expressed in pancreas. {ECO:0000269|PubMed:17442889}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12745364 rs766752243 |
| Subcellular location [CC] | [Isoform 1]: Golgi apparatus lumen {ECO:0000250|UniProtKB:Q61112}.; [Isoform 5]: Cytoplasm {ECO:0000269|PubMed:17442889}. Cell membrane {ECO:0000269|PubMed:17442889}. Cell projection, bleb. Note=Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs. {ECO:0000269|PubMed:17442889}. |
| Mouse PG classification | NA |
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