| Gene Information | |
|---|---|
| Gene Name | SDCCAG8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 713 |
| Protein Names | Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000054282 ) 3 ( ENSG00000276111 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86SQ7 |
| Gene Card | SDCCAG8 |
| Uniprot ID | Q86SQ7 |
| Pfam | PF15964 |
| In ASD | no |
| Allosteric Prediction | no (-0.463384754) |
| Ortholog in Animals | Alpaca_ SDCCAG8 ( ortholog_one2one ) Dog_ SDCCAG8 ( ortholog_one2one ) GuineaPig_ SDCCAG8 ( ortholog_one2one ) Macaque_ SDCCAG8 ( ortholog_one2one ) Mouse_ Sdccag8 ( ortholog_one2one ) Pig_ SDCCAG8 ( ortholog_one2one ) Rat_ Sdccag8 ( ortholog_one2one ) Rabbit_ SDCCAG8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | zone.of.skin |
| Tissue Specificity | Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors. {ECO:0000269|PubMed:9610721}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs2275155 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:27224062}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:27224062}. Cell junction. Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.; [Isoform 2]: Cytoplasm. |
| Mouse PG classification | NA |
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