| Gene Information | |
|---|---|
| Gene Name | SOX7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Transcription factor SOX-7 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000171056 ) 3 ( ENSG00000285438 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BT81 |
| Gene Card | SOX7 |
| Uniprot ID | Q9BT81 |
| Pfam | PF00505; PF12067 |
| In ASD | no |
| Allosteric Prediction | no (-1.308358159) |
| Ortholog in Animals | Alpaca_ SOX7 ( ortholog_one2one ) Dog_ SOX7 ( ortholog_one2one ) GuineaPig_ SOX7 ( ortholog_one2one ) Mouse_ Sox7 ( ortholog_one2one ) Pig_ SOX7 ( ortholog_one2one ) Rat_ Sox7 ( ortholog_one2one ) Rabbit_ SOX7 ( ortholog_one2one ) |
| Ohnologs | SOX18, SOX17 |
| Paralogs | SOX12, SOX17, SOX13, SOX30, CFAP65, SOX21, SOX8, SOX5, SOX14, SOX6, SOX9, SRY, SOX10, SOX1, SOX4, SOX18, SOX11, SOX3, SOX2, SOX15 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. {ECO:0000269|PubMed:11691915, ECO:0000269|PubMed:18819930}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. Cytoplasm {ECO:0000269|PubMed:18819930}. |
| Mouse PG classification | NA |
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