| Gene Information | |
|---|---|
| Gene Name | SDC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 198 |
| Protein Names | Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000124145 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P31431 |
| Gene Card | SDC4 |
| Uniprot ID | P31431 |
| Pfam | PF01034 |
| In ASD | no |
| Allosteric Prediction | no (-0.112588403) |
| Ortholog in Animals | Alpaca_ SDC4 ( ortholog_one2one ) Dog_ SDC4 ( ortholog_one2one ) GuineaPig_ SDC4 ( ortholog_one2one ) Macaque_ SDC4 ( ortholog_one2one ) Mouse_ Sdc4 ( ortholog_one2one ) Rat_ Sdc4 ( ortholog_one2one ) Rabbit_ SDC4 ( ortholog_one2one ) |
| Ohnologs | SDC1, SDC2 |
| Paralogs | SDC2, SDC1, SDC3 |
| Tissue | NA |
| Tissue Specificity | Expressed in epithelial and fibroblastic cells. {ECO:0000269|PubMed:1500433}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.070650(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EJP (NMR - ) 1EJQ (NMR - ) 1OBY (X-ray 1.85A ) 1YBO (X-ray 2.30A ) |
| DBSNP | rs2228384 |
| Subcellular location [CC] | [Isoform 1]: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:9169435}. Note=Shedding of the ectodomain produces a soluble form. {ECO:0000269|PubMed:9169435}.; [Isoform 2]: Secreted. |
| Mouse PG classification | NA |
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