| Gene Information | |
|---|---|
| Gene Name | KHDRBS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 443 |
| Protein Names | KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000121774 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q07666 |
| Gene Card | KHDRBS1 |
| Uniprot ID | Q07666 |
| Pfam | PF00013; PF16274; PF16568 |
| In ASD | no |
| Allosteric Prediction | yes (0.164477117) |
| Ortholog in Animals | Alpaca_ KHDRBS1 ( ortholog_one2one ) Dog_ KHDRBS1 ( ortholog_one2one ) GuineaPig_ KHDRBS1 ( ortholog_one2one ) Macaque_ KHDRBS1 ( ortholog_one2one ) Mouse_ Khdrbs1 ( ortholog_one2one ) Pig_ KHDRBS1 ( ortholog_one2one ) Rat_ Khdrbs1 ( ortholog_one2one ) Rabbit_ KHDRBS1 ( ortholog_one2one ) |
| Ohnologs | KHDRBS2, KHDRBS3 |
| Paralogs | KHDRBS3, SF1, KHDRBS2, QKI |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in all tissue examined. Isoform 1 is expressed at lower levels in brain, skeletal muscle, and liver whereas isoform 3 is intensified in skeletal muscle and in liver. {ECO:0000269|PubMed:9013542}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002479(Rat);0.045833(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XA6 (NMR - ) 3QHE (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:1374686, ECO:0000269|PubMed:29496907}. Cytoplasm {ECO:0000269|PubMed:29496907}. Membrane {ECO:0000269|PubMed:1374686}. Note=Predominantly located in the nucleus but also located partially in the cytoplasm. {ECO:0000269|PubMed:29496907}. |
| Mouse PG classification | NA |
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