| Gene Information | |
|---|---|
| Gene Name | SCYL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 742 |
| Protein Names | Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000000457 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IZE3 |
| Gene Card | SCYL3 |
| Uniprot ID | Q8IZE3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.305947517) |
| Ortholog in Animals | Alpaca_ SCYL3 ( ortholog_one2one ) Dog_ SCYL3 ( ortholog_one2one ) GuineaPig_ SCYL3 ( ortholog_one2one ) Macaque_ SCYL3 ( ortholog_one2one ) Mouse_ Scyl3 ( ortholog_one2one ) Pig_ SCYL3 ( ortholog_one2one ) Rat_ Scyl3 ( ortholog_one2one ) Rabbit_ SCYL3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCYL1, SCYL2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12651155}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12143301 rs4656197 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12651155}. Golgi apparatus {ECO:0000269|PubMed:12651155}. Cell projection, lamellipodium {ECO:0000269|PubMed:12651155}. Note=Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. |
| Mouse PG classification | NA |
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