| Gene Information | |
|---|---|
| Gene Name | MS4A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | High affinity immunoglobulin epsilon receptor subunit beta (FcERI) (Fc epsilon receptor I beta-chain) (IgE Fc receptor subunit beta) (Membrane-spanning 4-domains subfamily A member 2) |
| Target Name | high affinity immunoglobulin epsilon receptor subunit beta |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000149534 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q01362 |
| Gene Card | MS4A2 |
| Uniprot ID | Q01362 |
| Pfam | PF04103 |
| In ASD | no |
| Allosteric Prediction | no (-0.10400539) |
| Ortholog in Animals | Alpaca_ MS4A2 ( ortholog_one2one ) Dog_ MS4A2 ( ortholog_one2one ) GuineaPig_ MS4A2 ( ortholog_one2one ) Macaque_ MS4A2 ( ortholog_one2one ) Mouse_ Ms4a2 ( ortholog_one2one ) Pig_ MS4A2 ( ortholog_one2one ) Rat_ Ms4a2 ( ortholog_one2one ) Rabbit_ MS4A2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MS4A12, MS4A6E, MS4A6A, MS4A7, MS4A10, MS4A1, MS4A8, MS4A15, TMEM212, MS4A13, MS4A5, MS4A18, MS4A4E, MS4A4A, MS4A3, MS4A14 |
| Tissue | NA |
| Tissue Specificity | Found on the surface of mast cells and basophils. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35033981 rs535630 rs569108 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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