| Gene Information | |
|---|---|
| Gene Name | NLRC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1065 |
| Protein Names | NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000167984 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7RTR2 |
| Gene Card | NLRC3 |
| Uniprot ID | Q7RTR2 |
| Pfam | PF13516; PF05729; PF17776; PF17779 |
| In ASD | no |
| Allosteric Prediction | no (-0.809814269) |
| Ortholog in Animals | Alpaca_ NLRC3 ( ortholog_one2one ) Dog_ NLRC3 ( ortholog_one2one ) GuineaPig_ NLRC3 ( ortholog_one2one ) Macaque_ NLRC3 ( ortholog_one2one ) Mouse_ Nlrc3 ( ortholog_one2one ) Pig_ NLRC3 ( ortholog_one2one ) Rat_ Nlrc3 ( ortholog_one2one ) Rabbit_ NLRC3 ( ortholog_one2one ) |
| Ohnologs | NLRP12, NLRP5, NLRC5, NLRP14, NOD2 |
| Paralogs | NLRP9, NLRC5, NLRP14, NLRP7, NLRP4, CIITA, NOD1, NLRP8, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRP2, PYDC2, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | appendix, lymph.node, spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8057436 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15705585, ECO:0000269|PubMed:24560620, ECO:0000269|PubMed:25277106}. |
| Mouse PG classification | NA |
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