| Gene Information | |
|---|---|
| Gene Name | THOP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 689 |
| Protein Names | Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000172009 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P52888 |
| Gene Card | THOP1 |
| Uniprot ID | P52888 |
| Pfam | PF01432 |
| In ASD | no |
| Allosteric Prediction | no (-0.211703307) |
| Ortholog in Animals | Alpaca_ THOP1 ( ortholog_one2one ) Dog_ THOP1 ( ortholog_one2one ) GuineaPig_ THOP1 ( ortholog_one2one ) Macaque_ THOP1 ( ortholog_one2one ) Mouse_ Thop1 ( ortholog_one2one ) Pig_ THOP1 ( ortholog_one2one ) Rat_ Thop1 ( ortholog_one2one ) |
| Ohnologs | NLN |
| Paralogs | NLN, MIPEP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1S4B (X-ray 2.00A ) 2O36 (X-ray 1.95A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P47788}. |
| Mouse PG classification | NA |
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